ScienceDaily Health Headlines -- for Wednesday, October 12, 2011

ScienceDaily Health Headlines

for Wednesday, October 12, 2011

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Folic acid in early pregnancy associated with reduced risk of severe language delay in children (October 12, 2011) -- Use of folic acid supplements by women in Norway in the period four weeks before to eight weeks after conception was associated with a reduced risk of the child having severe language delay at age three years, according to a new study. ... > full story

Emerging pharmaceutical platform may pose risks to retinal health, study suggests (October 12, 2011) -- An emerging pharmaceutical platform used in treating a variety of diseases may produce unintended and undesirable effects on eye function, according to a new study. ... > full story

Greater support is needed to tackle the serious emotional consequences of whistleblowing, study finds (October 12, 2011) -- Whistleblowing incidents can have a serious, long-term impact on people’s emotional well-being and colleagues and employers have a responsibility to support those involved. Alcohol problems, nightmares, paranoid behaviour at work and overwhelming distress were just some of the problems reported by whistleblowers and those they reported. However, a new study also stresses the important role that whistleblowing has played in large-scale inquiries that have led to improvements in healthcare safety and quality. ... > full story

Stem cells, signaling pathways identified in lung repair (October 12, 2011) -- Researchers have identified cells and signaling molecules that trigger the repair of injured lungs. The scientists report that destruction of lung tissue in mice induces smooth muscle cells surrounding the airways to secrete a protein known as fibroblast growth factor 10, which induces surviving epithelial cells in the airways to revert to a stem-cell state, proliferate, repair and repopulate the lining of the lungs. ... > full story

Why do cancer cells change their appearance? (October 12, 2011) -- Like snakes, tumor cells shed their skin. Cancer is not a static disease but during its development the disease accumulates changes to evade natural defenses adapting to new environmental circumstances, protecting against chemotherapy and radiotherapy and invading neighboring organs, eventually causing metastasis. Now researchers have identified a mechanism that explains this change. Tumors "shed their skin" because molecular switches called microRNAs -- responsible for maintaining epithelial appearance of cells -- turn off. ... > full story

Experts find continuous glucose monitoring beneficial in maintaining target blood glucose levels (October 12, 2011) -- Patients with diabetes face daily challenges in managing their blood glucose levels, and it has been postulated that patients could benefit from a system providing continuous real-time glucose readings. Experts have released a clinical practice guideline providing recommendations on settings where patients are most likely to benefit from continuous glucose monitoring. ... > full story

Medical safety net for undocumented patients (October 12, 2011) -- Researchers are exploring the ethical challenges that clinicians and organizations face when providing medical care to undocumented immigrants in the United States. Most of the estimated 11 million undocumented residents of the US have no health insurance and are ineligible for public insurance programs. They are prohibited from obtaining insurance under the 2010 Patient Protection and Affordable Care Act. ... > full story

Herbal supplements may cause dangerous drug interactions in orthopaedic surgery patients, study suggests (October 11, 2011) -- Complementary and alternative medical treatments such as herbal supplements have become increasingly popular in the United States, especially among older patients and those with chronic pain. However, many of these products can have serious and potentially harmful side effects when combined with medications prescribed during and after surgery, according to a review article. ... > full story

A safe vaccination for Alzheimer's disease? (October 11, 2011) -- Genetic factors influence the immune response to vaccinations for Alzheimer's disease, which are among the most promising avenues of treatment for the illness. Using a mice model, these factors were studied. ... > full story

More intersections mean less outdoor activity for children (October 11, 2011) -- High intersection density and well-connected streets in towns and cities may discourage children from being active and exercising outdoors, according to a new study. ... > full story

New drug target for Alzheimer's, stroke discovered (October 11, 2011) -- A tiny piece of a critical receptor that fuels the brain and without which sentient beings cannot live has been discovered by scientists as a promising new drug target for Alzheimer's and other neurodegenerative diseases. ... > full story

Water channels in the body help cells remain in balance (October 11, 2011) -- Water channels exist not only in nature – microscopical water channels are also present in the cells of the body, where they ensure that water can be transported through the protective surface of the cell. Scientists have discovered that one type of the body’s water channels can be modified such that it becomes more stable, which may be significant in the treatment of several diseases. ... > full story

Perils of polite misunderstandings (October 11, 2011) -- Your friend debuts a questionable haircut and asks what you think of it. Brutal honesty would definitely hurt his feelings, so what do you say? Most people in this situation would probably opt for a vague or evasive response, along the lines of "It's really unique!" or "It's so you!" Politeness helps us get through awkward social situations like these and makes it easier for us to maintain our relationships. ... > full story

Mushroom compound appears to improve effectiveness of cancer drugs, study suggests (October 11, 2011) -- A compound isolated from a wild, poisonous mushroom growing in a southwest China forest appears to help a cancer killing drug fulfill its promise, researchers report. ... > full story

Evidence points to potential roles for cognitive rehabilitation therapy in treating traumatic brain injury, but further research needed (October 11, 2011) -- There is some evidence about the potential value of cognitive rehabilitation therapy for treating traumatic brain injury. ... > full story

Fall market jitters a SAD thing: Less daylight in fall may lead to depressed markets (October 11, 2011) -- It's no surprise to researchers that financial market dips and crashes typically happen in the fall. Researchers now show that people who experience seasonal depression shun financial risk-taking during seasons with diminished daylight but are more willing to accept risk in spring and summer. Seasonal depression may be sufficiently powerful to move financial markets. ... > full story

Restless legs syndrome may raise high blood pressure risk in middle-aged women (October 11, 2011) -- Middle-aged women with restless legs syndrome have an increased risk of hypertension. As symptoms of restless legs syndrome increase, the prevalence of high blood pressure increases. ... > full story

Common antibiotic can have serious adverse reactions, review finds (October 11, 2011) -- A commonly prescribed antimicrobial -- trimethoprim-sulfamethoxazole -- that has been used since 1968 can cause serious adverse reactions and physicians need to be aware of these in prescribing, states a new review. ... > full story

Health benefits of broccoli require the whole food, not supplements (October 11, 2011) -- New research has found that if you want some of the many health benefits associated with eating broccoli or other cruciferous vegetables, you need to eat the real thing -- a key phytochemical in these vegetables is poorly absorbed and of far less value if taken as a supplement. ... > full story

Certain dietary supplements associated with increased risk of death in older women, study suggests (October 11, 2011) -- Consuming dietary supplements, including multivitamins, folic acid, iron and copper, among others, appears to be associated with an increased risk of death in older women, according to a new report. ... > full story

Seeking superior stem cells: 100-fold increase in efficiency in reprogramming human cells to induced stem cells (October 11, 2011) -- Researchers have announced a new technique to reprogram human cells into stem cells. Their process increases the efficiency of reprogramming by 100-fold and generates cells of a higher quality at a faster rate. By adding two protein factors to the current mix of four, scientists brought about dramatic improvement in the efficiency of reprogramming and the robustness of stem cell development. ... > full story

Experimental vaccine protects monkeys from blinding trachoma (October 11, 2011) -- An attenuated, or weakened, strain of Chlamydia trachomatis bacteria can be used as a vaccine to prevent or reduce the severity of trachoma, the world's leading cause of infectious blindness, suggest new findings from a study in monkeys. ... > full story

Exercise just as good as drugs at preventing migraines, Swedish study suggests (October 11, 2011) -- Although exercise is often prescribed as a treatment for migraine, there has not previously been sufficient scientific evidence that it really works. However, research from Sweden has now shown that exercise is just as good as drugs at preventing migraines. ... > full story

Family history may have more important role than previously thought in development of Alzheimer disease (October 11, 2011) -- Family history of Alzheimer disease is associated with several age-related changes that appear to influence Alzheimer disease (AD) biomarker abnormalities beyond the increased risk of the APOE4 gene, according to a new report. ... > full story

Gene signature predicts oral cancer recurrence (October 11, 2011) -- Oral squamous cell carcinoma (OSCC) is responsible for nearly a quarter of all head and neck cancers. It is one of the leading causes of cancer death -- largely due to the failure of current histological procedures in predicting the recurrence of the disease. New research shows that a four-gene signature may accurately predict which patients are at higher risk of OSCC recurrence. ... > full story

College football players can cry (a little) if they want to (October 11, 2011) -- While there's no crying in baseball, as Tom Hanks' character famously proclaimed in "A League of Their Own," crying in college football might not be a bad thing, at least in the eyes of one's teammates. ... > full story

How the brain makes memories: Rhythmically (October 11, 2011) -- The brain learns through changes in the strength of synapses -- the connections between neurons -- in response to stimuli. Now, researchers have found there is an optimal brain rhythm, or timing, for changing synaptic strength, and hence learning. ... > full story

Crossing legs after severe stroke may be a good sign of recovery (October 11, 2011) -- People who are able to cross their legs soon after having a severe stroke appear to be more likely to have a good recovery compared to people who can't cross their legs. That's according to new research. ... > full story

Scientists discover three new gene faults which could increase melanoma risk by 30 percent (October 11, 2011) -- Researchers have discovered the first DNA faults linked to melanoma -- the deadliest skin cancer -- that are not related to hair, skin or eye color. ... > full story

New insight into the cellular defects in Huntington's disease (October 11, 2011) -- Huntington disease is a devastating neurogenerative disorder caused by a mutant HTT gene. Although this has been known for many years, the functions of normal Htt protein and the mechanisms by which mutant Htt protein causes disease are not well understood. But now, researchers have now uncovered a new function for normal Htt protein and determined that this function is disrupted in a mouse model of Huntington's disease and in patients with the disorder. ... > full story

Alzheimer disease: Medication gantenerumab associated with reduction in brain amyloid levels related to AD, small study finds (October 11, 2011) -- Although it is a small study and more clinical trials are needed, treatment with the medication gantenerumab appeared to result in a reduction in brain amyloid levels in patients with Alzheimer disease, according to a new report. ... > full story

Combination therapies for drug-resistant cancers (October 11, 2011) -- Some cancers can be effectively treated with drugs inhibiting proteins known as receptor tyrosine kinases, but not those cancers caused by mutations in the KRAS gene. However, researchers have now identified a potential way to effectively use receptor tyrosine kinases inhibitors to treat individuals with KRAS mutant colorectal cancers -- combine them with inhibitors of the MEK/ERK signaling pathway. ... > full story

Behavioral and educational interventions appear to be effective for patients with poorly controlled diabetes (October 11, 2011) -- Three randomized controlled trials examine the effectiveness of behavioral and educational interventions for patients with poorly controlled diabetes. ... > full story

Research examines the economic value of on-premise signs (October 11, 2011) -- Good signage holds benefits for both businesses and their customers. But what qualifies as good signs? ... > full story

Annual cost of violence pegged at .9 billion after women leave abusive partners (October 11, 2011) -- Even after women have separated from an abusive partner, the violence still costs Canadians an estimated .9 billion a year, according to new research. ... > full story

Inhaler treatment for lung cancer (October 11, 2011) -- Lung cancer patients could receive safer and more efficient treatment through a new system. ... > full story

Hispanic women have higher incidence of rare breast tumor (October 11, 2011) -- According to a new study, phyllodes tumors -- rare breast malignancies accounting for 0.5 to 1 percent of all breast tumors -- tend to be more prevalent in Hispanic patients. Population-based estimates indicate that the incidence of malignant phyllodes tumors is 2.1 cases per million women, with the highest frequencies in Hispanic women. ... > full story

New testing program improves scores, knowledge retention for third-year internal medicine residents (October 11, 2011) -- A new analysis shows that a multiple-choice testing program coupled with a novel year-long clinical experience helps internal medicine residents improve their scores on the Internal Medicine In-Training Exam. ... > full story

Ticagrelor: Considerable added benefit for specific patients, study suggests (October 11, 2011) -- Since the start of 2011, the active ingredient ticagrelor can be prescribed in Germany in addition to acetylsalicylic acid to avoid blood clots in patients with acute ischaemia of the cardiac muscle. Experts suggest that ticagrelor provides considerable added benefit to specific patients by decreasing the risk of death and myocardial infarction. ... > full story

Small molecules can starve cancer cells (October 10, 2011) -- Researchers in Denmark have found that a small molecule in our cells can block autophagy in cancer cells making them more sensitive for treatment. ... > full story

Study shows how bookmarking genes pre-cell division hastens their subsequent reactivation (October 10, 2011) -- By observing and measuring the kinetics of activation of a single gene locus in a cell before it divides and comparing it with the same gene's reactivation in newly formed daughter cells, scientists have discovered how how bookmarking a gene pre-division causes it to get reactivated post-division. ... > full story

Novel technique uses RNA interference to block inflammation (October 10, 2011) -- Researchers have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. ... > full story

Older cancer survivor population to increase substantially, report predicts (October 10, 2011) -- Over the next decade, the population of cancer survivors over 65 years of age will increase by approximately 42 percent, according to a new report. ... > full story

If you don't snooze, do you lose? Wake-sleep patterns affect brain synapses during adolescence (October 10, 2011) -- An ongoing lack of sleep during adolescence could lead to more than dragging, foggy teens, a new study suggests. ... > full story

Sniffing out the brain's predictive power: Human brain 'smells' what it expects rather than what it sniffs (October 10, 2011) -- In the moments before you "stop and smell the roses," it's likely your brain is already preparing your sensory system for that familiar floral smell. New research offers strong evidence that the brain uses predictive coding to generate "predictive templates" of specific smells -- setting up a mental expectation of a scent before it hits your nostrils. ... > full story

New membrane lipid measuring technique may help fight disease (October 10, 2011) -- Chemists have developed a technique which successfully quantifies signaling lipids on live cell membranes in real time, opening up possible new routes for treating diseases. ... > full story

Detecting glaucoma before it blinds (October 10, 2011) -- Early detection and diagnosis of open angle glaucoma important so that treatment can be used in the early stages of the disease developing to prevent or avoid further vision loss. Researchers in the US have analyzed and ranked the various risk factors for open angle glaucoma so that patients can be screened at an earlier stage if they are more likely to develop the condition. ... > full story

Blame 'faulty' frontal lobe function for undying optimism in face of reality (October 10, 2011) -- Why, in the face of clear evidence to suggest to the contrary, do some people remain so optimistic about the future? Researchers have shown that people who are very optimistic about the outcome of events tend to learn only from information that reinforces their rose-tinted view of the world. This is related to "faulty" function of their frontal lobes. ... > full story


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