ScienceDaily Health Headlines -- for Wednesday, November 30, 2011

ScienceDaily Health Headlines

for Wednesday, November 30, 2011

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Transplanted cells repair the brain in obese mice (November 30, 2011) -- Small numbers of properly selected neurons, transplanted into damaged brain areas in mice, are capable of restoring lost functions. Experiments on mice with a defect resulting in obesity and a series of measurements documenting efficiency of the neuron transplant method have now been carried out. ... > full story

Injection lowers cholesterol in preliminary human trial (November 30, 2011) -- Patients unable to control their cholesterol levels with medications may someday be able to lower their "bad" cholesterol with a shot, according to new research. ... > full story

Pneumonia most common infection after heart surgery (November 30, 2011) -- Pneumonia -- not a deep incision surgical site infection -- is the most common serious infection after heart surgery, according to new research. ... > full story

Mood, cognition and sleep patterns improve in Alzheimer's patients after cataract surgery, study finds (November 30, 2011) -- Researchers in France have found that patients with mild Alzheimer's disease whose vision improved after cataract surgery also showed improvement in cognitive ability, mood, sleep patterns and other behaviors. ... > full story

Researchers develop more effective way to discover and test potential cancer drugs (November 30, 2011) -- Researchers have created a new phenotypic screening platform that better predicts success of drugs developed to prevent blood vessel tumor growth when moving out of the lab and onto actual tumors. ... > full story

Antifolates show promise against NSCLC subtype (November 30, 2011) -- Patients with non-small cell lung cancer who have mutations in the KRAS gene should respond well to the antifolate class of drugs, according to results of a recent study comparing human lung cancer cell lines and patients. ... > full story

Babies embrace punishment earlier than previously thought, study suggests (November 29, 2011) -- Babies as young as eight months want people who commit or condone antisocial acts to be punished, according to a new study. While previous research shows that babies uniformly prefer kind acts, the new study suggests that eight-month-old infants support negative behavior if it is directed at those with antisocial behavior -- and dislike those who are nice to bad guys. ... > full story

High blood sugar levels in older women linked to colorectal cancer (November 29, 2011) -- Elevated blood sugar levels are associated with an increased risk of colorectal cancer, according to a new study. The findings were observed in nearly 5,000 postmenopausal women. ... > full story

Drug-eluting balloons are a promising tool in treatment of narrowed metal stents and in patients at high risk for bleeding complications (November 29, 2011) -- A drug-coated balloon inserted in a narrowed bare metal stent is a promising therapy for restoring blood flow, according to new research. ... > full story

Immune system has protective memory cells, researchers discover (November 29, 2011) -- The immune system possesses a type of cell that can be activated by tissues within the body to remind the immune system not to attack our own molecules, cells and organs, researchers have discovered. ... > full story

Scientists identify treatable weakness in lethal form of prostate cancer (November 29, 2011) -- A recent report suggests that a new treatment may be on the horizon for neuroendocrine prostate cancers, the most lethal subtype of this disease. ... > full story

Crash experts find car seats protect overweight kids, too (November 29, 2011) -- Researchers have found no evidence of increased injury risk among crash-involved children across a broad weight range, when they were properly restrained in the correct child safety seat or booster seat for their height and weight. ... > full story

Is there a central brain area for hearing melodies and speech cues? Still an open question (November 29, 2011) -- Previous studies have suggested a particular hotspot in the brain might be responsible for perceiving pitch, but auditory neuroscientists are still debating whether this "pitch center" actually exists. A review article discusses a recent study claiming that this pitch center may not exist after all, or may not be located where previous research has suggested. ... > full story

Environment and diet leave their prints on the heart (November 29, 2011) -- A new study, which set out to investigate DNA methylation in the human heart and the "missing link" between our lifestyle and our health, has now mapped the link in detail across the entire human genome. ... > full story

Frequent 'heading' in soccer can lead to brain injury and cognitive impairment (November 29, 2011) -- Using advanced imaging techniques and cognitive tests, researchers have shown that repeatedly heading a soccer ball increases the risk for brain injury. ... > full story

Gene acts as a brake on breast cancer progression (November 29, 2011) -- New research provides compelling new evidence that a gene known as 14-3-3sigma plays a critical role in halting breast cancer initiation and progression. ... > full story

Seeking to be the 'perfect parent' not always good for new moms and dads (November 29, 2011) -- Parents of newborns show poorer adjustment to their new role if they believe society expects them to be "perfect" moms and dads, a new study shows. Moms showed less confidence in their parenting abilities and dads felt more stress when they were more worried about what other people thought about their parenting skills. ... > full story

A first: Lab creates cells used by brain to control muscle cells (November 29, 2011) -- Researchers, for the first time, have used stem cells to grow neuromuscular junctions between human muscle cells and human spinal cord cells, the key connectors used by the brain to communicate and control muscles in the body. ... > full story

Coffee may protect against endometrial cancer, study suggests (November 29, 2011) -- Long-term coffee consumption may be associated with a reduced risk for endometrial cancer, according to a recent study. ... > full story

Mid-afternoon slump? Why a sugar rush may not be the answer (November 29, 2011) -- A new study has found that protein and not sugar activates the cells responsible for keeping us awake and burning calories. The research has implications for understanding obesity and sleep disorders. ... > full story

Boys with regressive autism, but not early onset autism, have larger brains than age-matched healthy counterparts, study finds (November 29, 2011) -- In the largest study of brain development in preschoolers with autism to date, researchers have found that three-year-old boys with regressive autism, but not early onset autism, have larger brains than their healthy counterparts. ... > full story

Scientists determine how antibody recognizes key sugars on HIV surface (November 29, 2011) -- HIV is coated in sugars that usually hide the virus from the immune system. Newly published research reveals how one broadly neutralizing HIV antibody actually uses part of the sugary cloak to help bind to the virus. The antibody binding site, called the V1/V2 region, represents a suitable HIV vaccine target, according to the scientists who conducted the study. ... > full story

Low-income older adults more likely to develop heart failure (November 29, 2011) -- The odds of having heart failure appear to be higher in seniors with a low income -- even among those with a college or higher education -- according to new research. ... > full story

New technique puts chemistry breakthroughs on the fast track (November 29, 2011) -- Scientists can now take that "a-ha" moment to go with a new method developed -- and successfully tested -- to accomplish "accelerated serendipity" and speed up the chances of an unexpected yet groundbreaking chemical discovery. ... > full story

Drug may slow spread of deadly eye cancer (November 29, 2011) -- A drug commonly used to treat seizures appears to make eye tumors less likely to grow if they spread to other parts of the body, according to researchers. ... > full story

Study evaluates association between urinary salt excretion and risk of cardiovascular events or death (November 29, 2011) -- For persons with cardiovascular disease or diabetes, urinary sodium excretion (a surrogate for salt intake) at higher levels or at lower levels compared to mid-range values was associated with an increased risk of cardiovascular events (for higher levels) or cardiovascular death and hospitalization for congestive heart failure (for lower levels), according to a new study. Also, higher estimated urinary potassium excretion was associated with a reduced risk of stroke. ... > full story

How the brain strings words into sentences (November 29, 2011) -- Distinct neural pathways are important for different aspects of language processing, researchers have discovered, studying patients with language impairments caused by neurodegenerative diseases. ... > full story

Most hospitals miss critical window for heart attack transfer patients, study finds (November 29, 2011) -- Most heart attack patients transferred between hospitals for the emergency artery-opening procedure called angioplasty are not transported as quickly as they should be, researchers report in the first national study of "door-in door-out" time for transfer patients. ... > full story

Nearly 10 percent of patients undergoing procedure such as balloon angioplasty or stent placement readmitted to hospital within 30 days (November 29, 2011) -- In an analysis of the outcomes for more than 15,000 patients who underwent a percutaneous coronary intervention (PCI; procedures such as balloon angioplasty or stent placement used to open narrowed coronary arteries), nearly one in 10 were readmitted to the hospital within 30 days, and these patients had a higher risk of death within one year, according to a new study. Various factors were associated with hospital readmission, including female sex, Medicare insurance, unstable angina and others. ... > full story

Spinal bleeding with brain injury may suggest abuse in young children (November 29, 2011) -- A new study found that spinal bleeding is found often in young children who are victims of abusive trauma. The findings support performing complete spine imaging for children undergoing brain magnetic resonance imaging for moderate or severe traumatic brain injury and suggest a pathway for distinguishing between abusive and accidental injury. ... > full story

Key area that could sever communication between brain and heart in disease identified (November 29, 2011) -- A team of neuroscientists and anesthetists, who have been using pioneering techniques to study how the brain regulates the heart, has identified a crucial part of the nervous system whose malfunction may account for an increased risk of death from heart failure. The findings could lead to more targeted therapies to help reduce serious illness and death in cardiovascular disease. ... > full story

Among patients with infective endocarditis and heart failure, valvular surgery associated with reduced mortality (November 29, 2011) -- Among patients with infective endocarditis and heart failure, about two-thirds undergo valvular surgery, which is associated with a significant reduction in the risk of death in the hospital and at one year, according to a new study. ... > full story

40 percent of youths attempting suicide make first attempt before high school, study finds (November 29, 2011) -- Thoughts about killing oneself and engaging in suicidal behavior may begin much younger than previously thought. While about one of nine youths attempt suicide by the time they graduate from high school, new findings reveal that a significant proportion make their first suicide attempt in elementary or middle school. ... > full story

Depression can lead to heart disease, study suggests (November 28, 2011) -- Depression may have more far-reaching consequences than previously believed. Recent data suggests that individuals who suffer from a mood disorder could be twice as likely to have a heart attack compared to individuals who are not depressed. ... > full story

Biopsy of recurrent breast cancer can alter treatment, new study shows (November 28, 2011) -- A recent clinical research study by breast cancer specialists has again proven that comparing a new biopsy of progressing or recurring cancer with that of the original cancer can dictate a change in treatment. ... > full story

Study looks at the nature of change in our aging, changing brains (November 28, 2011) -- As we get older, our cognitive abilities change, improving when we're younger and declining as we age. Scientists posit a hierarchical structure within which these abilities are organized. There's the "lowest" level -- measured by specific tests, such as story memory or word memory; the second level, which groups various skills involved in a category of cognitive ability, such as memory, perceptual speed, or reasoning; and finally, the "general," or G, factor, a sort of statistical aggregate of all the thinking abilities. What happens to this structure as we age? ... > full story

Aging stem cells may explain higher prevalence of leukemia, infections among elderly (November 28, 2011) -- Human stem cells aren't immune to the aging process, according to scientists. Researchers studied hematopoietic stem cells, which create the cells that comprise the blood and immune system. Understanding when and how these stem cells begin to falter as the years pass may explain why some diseases, such as acute myeloid leukemia, increase in prevalence with age, and also why elderly people tend to be more vulnerable to infections such as colds and the flu. ... > full story

Integrated 3-D imaging facilitates human face transplantation (November 28, 2011) -- By combining conventional medical imaging with some of the same 3-D modeling techniques used in Hollywood blockbusters, researchers are offering new hope to victims of serious facial injuries who may be candidates for human facial transplants. ... > full story

An unexpected player in a cancer defense system (November 28, 2011) -- Researchers have identified a new protein involved in a defense mechanism against cancer. The VCP/p97 complex is best known for its role in protein destruction and is involved in a type of familial dementia and ALS. In a novel study the researchers now describe how this complex also plays an important role in regulating the recruitment of the tumor suppressor protein 53BP1 to damaged DNA -- suggesting an important role for VCP/p97 in our body's defense against cancer. ... > full story

Smoking cessation interventions appear to be effective for some current smokers (November 28, 2011) -- Nicotine replacement therapy and smoking cessation intervention programs are associated with positive outcomes among current smokers, according to new studies. ... > full story

New compound defeats drug-resistant bacteria (November 28, 2011) -- Chemists have synthesized a new compound that makes drug-resistant bacteria susceptible again to antibiotics. The compound -- BU-005 -- blocks pumps that a bacterium employs to expel an antibacterial agent called chloramphenicol. The team used a new and highly efficient method for the synthesis of BU-005 and other C-capped dipetptides. ... > full story

Cleft lip corrected genetically in mouse model (November 28, 2011) -- Scientists have used genetic methods to successfully repair cleft lips in mice embryos specially engineered for the study of cleft lip and cleft palate. The research breakthrough may show the way to prevent or treat the conditions in humans. ... > full story

Moderate alcohol consumption is associated with small intestinal bacterial overgrowth, study finds (November 28, 2011) -- Just one drink per day for women -- two for men -- could lead to small intestinal bacterial overgrowth and subsequently cause gastrointestinal symptoms like bloating, gas, abdominal pain, constipation and diarrhea, according to the results of a new study. ... > full story

New handle makes lifting infant car seats safer, easier (November 28, 2011) -- Engineers have developed a new handle for infant car seats that makes it easier for parents to lift the seat out of a car -- while retaining a firmer grip on the handle -- making it less likely that the seat will be dropped. ... > full story

Creative excuses: Original thinkers more likely to cheat, study finds (November 28, 2011) -- Creative people are more likely to cheat than less creative people, possibly because this talent increases their ability to rationalize their actions, according to new research. ... > full story

Vaccine prototype stronger than traditional vaccines (November 28, 2011) -- Researchers have created a vaccine that is more potent than traditional vaccines available today. The glycoconjugate vaccine prototype is 100 times more effective than traditional glycoconjugate vaccines. ... > full story

Researchers find regulatory T-cell clue to help prevent GVHD (November 28, 2011) -- Graft-versus-host disease (GVHD) is a serious risk in many kinds of cell transplants, including for stem cell transplants carried out when stem cells are partially depleted of conventional T cells, which play an important role in the immune system. Now, researchers have tested a process by which T regulatory cells can be "expanded" to help prevent GVHD. ... > full story

Mid-morning snacking may sabotage weight-loss efforts (November 28, 2011) -- Women dieters who grab a snack between breakfast and lunch lose less weight compared to those who abstain from a mid-morning snack, according to a new study. ... > full story


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