ScienceDaily Health Headlines -- for Thursday, February 23, 2012

ScienceDaily Health Headlines

for Thursday, February 23, 2012

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Is there a general motivation center in the depths of the brain? (February 22, 2012) -- Researchers have identified the part of the brain driving motivation during actions that combine physical and mental effort: the ventral striatum. ... > full story

Faster way to catch cells: New microfluidic device could be used to diagnose and monitor cancer and other diseases (February 22, 2012) -- Separating complex mixtures of cells, such as those found in a blood sample, can offer valuable information for diagnosing and treating disease. However, it may be necessary to search through billions of other cells to collect rare cells such as tumor cells, stem cells or fetal cells. Researchers have now demonstrated a new microfluidic device that can isolate target cells much faster than existing devices. Such technology could be used in applications such as point-of-care diagnostics and personalized medicine. ... > full story

New way to tap largest remaining treasure trove of potential new antibiotics (February 22, 2012) -- Scientists are reporting use of a new technology for sifting through the world's largest remaining pool of potential antibiotics to discover two new antibiotics that work against deadly resistant microbes, including the "superbugs" known as MRSA. ... > full story

Researchers take a step forward in transplanting pig cells to regenerate human cartilage (February 22, 2012) -- Researchers have recently studied the response of human NK cells against porcine chondrocytes. The results of the research indicate that these cells, characteristic of the innate immune system, play an important role in the rejection of xenotransplantation of porcine chondrocytes. ... > full story

Exposure to micronutrients pre-pregnancy associated with gene modifications in offspring (February 22, 2012) -- The offspring of women who were given micronutrient supplements (minerals needed in small quantities, such as iron, iodine and vitamin A) before they became pregnant had gene modifications at birth as well as when they were tested at nine months. ... > full story

Heart beats to the rhythm of a circadian clock (February 22, 2012) -- Sudden cardiac death -- catastrophic and unexpected fatal heart stoppage -- is more likely to occur shortly after waking in the morning and in the late night. In a new study, an international consortium of researchers explains the molecular linkage between the circadian clock and the deadly heart rhythms that lead to sudden death. ... > full story

World of Warcraft boosts cognitive functioning in older adults (February 22, 2012) -- For some older adults, the online video game World of Warcraft (WoW) may provide more than an opportunity for escapist adventure. Researchers have found that playing WoW boosted cognitive functioning for older adults – particularly those who had scored poorly on cognitive ability tests before playing the game. ... > full story

How cancer cells change once they spread to distant organs (February 22, 2012) -- Oncologists have known that in order for cancer cells to spread, they must transform themselves so they can detach from a tumor and spread to a distant organ. Now, scientists have revealed critical steps in what happens next -- how these cells reverse the process, morphing back into classical cancer that can now grow into a new tumor. ... > full story

What can animals' survival instincts tell us about understanding human emotion? (February 22, 2012) -- Can animals’ survival instincts shed additional light on what we know about human emotion? Neuroscientists pose this question in outlining a pioneering theory, drawn from two decades of research, that could lead to a more comprehensive understanding of emotions in both humans and animals. ... > full story

Tiny, implantable medical device can propel itself through bloodstream (February 22, 2012) -- For 50 years, scientists had searched for the secret to making tiny implantable devices that could travel through the bloodstream. Engineers have now demonstrated a wirelessly powered device that just may make the dream a reality. ... > full story

Newly identified oral bacterium linked to heart disease and meningitis (February 22, 2012) -- A novel bacterium, thought to be a common inhabitant of the oral cavity, has the potential to cause serious disease if it enters the bloodstream, according to a new study. ... > full story

Fried food risks: Toxic aldehydes detected in reheated oil (February 22, 2012) -- Researchers have been the first to discover the presence of certain aldehydes in food, which are believed to be related to some neurodegenerative diseases and some types of cancer. These toxic compounds can be found in some oils, such as sunflower oil, when heated at a suitable temperature for frying. ... > full story

Off switch for pain? Chemists build light-controlled neural inhibitor (February 22, 2012) -- Pain? Just turn it off! It may sound like science fiction, but researchers have now succeeded in inhibiting pain-sensitive neurons on demand, in the laboratory. The crucial element in their strategy is a chemical sensor that acts as a light-sensitive switch. ... > full story

Fake drug sales are increasing on the Internet and turning up in legitimate supply chains, review finds (February 22, 2012) -- Criminal gangs are increasingly using the internet to market life-threatening counterfeit medicines and some have even turned up in legitimate outlets such as pharmacies, according to a newly published review. ... > full story

Neuroscientists identify how the brain works to select what we (want to) see (February 21, 2012) -- If you are looking for a particular object -- say a yellow pencil -- on a cluttered desk, how does your brain work to visually locate it? For the first time, neuroscientists have identified how different neural regions communicate to determine what to visually pay attention to and what to ignore. This finding is a major discovery for visual cognition and will guide future research into visual and attention deficit disorders. ... > full story

Cocaine and the teen brain: New insights into addiction (February 21, 2012) -- When first exposed to cocaine, the adolescent brain launches a strong defensive reaction designed to minimize the drug's effects, scientists have found. Now two new studies identify key genes that regulate this response and show that interfering with this reaction dramatically increases a mouse's sensitivity to cocaine. ... > full story

Stronger intestinal barrier may prevent cancer in the rest of the body, new study suggests (February 21, 2012) -- A leaky gut may be the root of some cancers forming in the rest of the body, a new study suggests. It appears that the hormone receptor guanylyl cyclase C (GC-C) -- a previously identified tumor suppressor that exists in the intestinal tract -- plays a key role in strengthening the body's intestinal barrier, which helps separate the gut world from the rest of the body, and possibly keeps cancer at bay. Without the receptor, that barrier weakens. ... > full story

How good cholesterol turns bad (February 21, 2012) -- Researchers have found new evidence to explain how cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol from "good" high density lipoproteins (HDLs) to "bad" low density lipoproteins (LDLs). These findings point the way to the design of safer, more effective next generation CETP inhibitors that could help prevent the development of heart disease. ... > full story

Anticipation of stressful situations accelerates cellular aging (February 21, 2012) -- The ability to anticipate future events allows us to plan and exert control over our lives, but it may also contribute to stress-related increased risk for the diseases of aging, according to a new study. ... > full story

Injectable gel could repair tissue damaged by heart attack (February 21, 2012) -- Researchers have developed a new injectable hydrogel that could be an effective and safe treatment for tissue damage caused by heart attacks. ... > full story

Cell energy sensor mechanism discovered (February 21, 2012) -- Researchers have discovered more details about how an energy sensing “thermostat” protein determines whether cells will store or use their energy reserves. The researchers have shown that a chemical modification on the thermostat protein changes how it’s controlled. Without the modification, cells use stored energy, and with it, they default to stockpiling resources. When cells don’t properly allocate their energy supply, they can die off or become cancerous. ... > full story

Can consuming caffeine while breastfeeding harm your baby? (February 21, 2012) -- Babies are not able to metabolize or excrete caffeine very well, so a breastfeeding mother's consumption of caffeine may lead to caffeine accumulation and symptoms such as wakefulness and irritability, according to an expert. ... > full story

Many young people don't know what constitutes sensible alcohol consumption (February 21, 2012) -- A new study reveals that young people do not possess the knowledge or skills required to adhere to U.S. government guidelines for responsible alcohol consumption. ... > full story

Noninvasive method accurately and efficiently detects risk of Down syndrome, researchers say (February 21, 2012) -- Using a noninvasive test on maternal blood that deploys a novel biochemical assay and a new algorithm for analysis, scientists can detect, with a high degree of accuracy, the risk that a fetus has the chromosomal abnormalities that cause Down syndrome and a genetic disorder known as Edwards syndrome. The new approach is more scalable than other recently developed genetic screening tests and has the potential to reduce unnecessary amniocentesis or CVS. ... > full story

Is fructose being blamed unfairly for obesity epidemic? (February 21, 2012) -- Is fructose being unfairly blamed for the obesity epidemic? Or do we just eat and drink too many calories? Researchers reviewed more than 40 published studies on whether the fructose molecule itself causes weight gain. In 31 "isocaloric" trials they reviewed, participants ate a similar number of calories, but one group ate pure fructose and the other ate non-fructose carbohydrates. The fructose group did not gain weight. ... > full story

Step forward in effort to regenerate damaged nerves (February 21, 2012) -- Scientists have taken a step forward toward the goal of repairing nerves in such patients more effectively. In a new study, researchers report that a surprising set of cells may hold potential for nerve transplants. ... > full story

Does depression contribute to the aging process? (February 21, 2012) -- Stress has numerous detrimental effects on the human body. Many of these effects are acutely felt by the sufferer, but many more go "unseen," one of which is shortening of telomere length. ... > full story

Molecular basis of touch sensation: Researchers identify new function of a well-known gene (February 21, 2012) -- A gene known to control lens development in mice and humans is also crucial for the development of neurons responsible for mechanosensory function, as neurobiologists have now discovered. They found that in mice in which they had removed the c-Maf gene in the nerve cells, touch sensation is impaired. This similarly applies to human carriers of a mutant c-Maf gene. ... > full story

Scientists unlock evolutionary secret of blood vessels (February 21, 2012) -- Scientists have shed light on how vertebrates evolved closed circulation systems designed to more effectively carry blood to organs and tissues. ... > full story

Brain makes call on which ear is used for cell phone (February 21, 2012) -- A new study finds a strong correlation between brain dominance and the ear used to listen to a cell phone, with more than 70 percent of participants holding their cell phone up to the ear on the same side as their dominant hand. ... > full story

Evolution of staph 'superbug' traced between humans and livestock (February 21, 2012) -- A strain of the potentially deadly antibiotic-resistant bacterium known as MRSA has jumped from livestock to humans, according to a new study. ... > full story

Implantable, wireless sensors share secrets of healing tissues (February 21, 2012) -- A new implantable sensor can wirelessly transmit data from the site of a recent orthopedic surgery. Inexpensive to make and highly reliable, this new sensor holds the promise of more accurate, more cost-effective, and less invasive post-surgery monitoring and diagnosis. ... > full story

Over-reactive parenting linked to negative emotions and problem behavior in toddlers (February 21, 2012) -- Researchers have found that parents of young children who anger easily and overreact are more likely to have toddlers who act out and become upset easily. ... > full story

Environmental pollutant level during pregnancy linked with grown daughters who are overweight (February 21, 2012) -- The levels of the environmental pollutant perfluorooctanoic acid (PFOA) that mothers had in their blood during pregnancy increased the risk of obesity in their daughters at 20 years of age. ... > full story

Gene affecting the ability to sleep discovered in fruit flies (February 20, 2012) -- On the surface, it's simple: when night falls, our bodies get sleepy. But behind the scenes, a series of complex molecular events, controlled by our genes, is hard at work to make us groggy. Now, research suggests that a newly identified gene known as insomniac may play a role in keeping us asleep. By cloning and testing this gene in fruit flies researchers say they have discovered an entirely new mechanism by which sleep is regulated. ... > full story

Babies' colic linked to mothers' migraines (February 20, 2012) -- A study of mothers and their young babies by neurologists has shown that mothers who suffer migraine headaches are more than twice as likely to have babies with colic than mothers without a history of migraines. ... > full story

Telomere failure, telomerase activation drive prostate cancer progression (February 20, 2012) -- Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those caps, allows malignant cells to evade destruction and acquire more deadly characteristics, researchers report. ... > full story

Blocking telomerase kills cancer cells but provokes resistance, progression (February 20, 2012) -- Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive and spread, scientists report. ... > full story

Traitorous immune cells promote sudden ovarian cancer progression (February 20, 2012) -- In a new mouse model that mimics the tumor microenvironment of ovarian cancer, scientists have demonstrated that ovarian tumors don't necessarily break "free" of the immune system, rather dendritic cells of the immune system seem to actively support the tumor's escape. The researchers show that it might be possible to restore the immune system by targeting a patient's own dendritic cells. ... > full story

World's longest kidney transplant chain completed (February 20, 2012) -- The world's longest living-donor kidney transplant chain has just been completed. The chain involved 30 donors, 30 recipients and 17 hospitals throughout the U.S. ... > full story

New treatment for traumatic brain injury shows promise in animals (February 20, 2012) -- A new drug is showing promise in shielding against the harmful effects of traumatic brain injury in rats, according to a new study. ... > full story

Rainforest plant combats multi-resistant bacterial strains (February 20, 2012) -- Aggressive infections in hospitals are an increasing health problem worldwide. The development of bacterial resistance is alarming. Now a young Danish scientist has found a natural substance in a Chilean rainforest plant that effectively supports the effect of traditional treatment with antibiotics. ... > full story

Home visits for asthma: A win for both patients and payers (February 20, 2012) -- Nearly one in 10 children have asthma, according to government statistics, and in low-income parts of Boston, nearly 16 percent of children are affected. A new program demonstrates the potential to dramatically reduce hospitalization and emergency department visits for asthma -- improving patient outcomes and saving .46 per dollar spent through reduced hospital utilization. ... > full story

Controlled dose of deadly carbon monoxide prevents miscarriage in mice (February 20, 2012) -- Heme oxygenase-1 is essential for the growth of blood vessels in the placenta and in establishing blood flow in the umbilical cord. Too little HO-1 can lead to a restriction in the growth of the fetus and even in fetal death and miscarriage. New research has shown that low dose carbon monoxide therapy is able to restore placental function and prevent fetal death in mice. The researcher warned, "It is very important, given the inherent dangers in using carbon monoxide, that the dose and length of treatment are tightly controlled." ... > full story

Neurodegenerative diseases: Ring-like structure found in 'elongator' protein complex (February 20, 2012) -- A ring-like structure found in a protein complex called ‘Elongator’ provides new clues to its tasks inside the cell and to its role in neurodegenerative diseases. It is the first three-dimensional structure of part of this complex. ... > full story

Tongue drive system goes inside the mouth to improve performance and user comfort (February 20, 2012) -- The Tongue Drive System is getting less conspicuous and more capable. The newest system prototype allows people with high-level spinal cord injuries to wear an inconspicuous dental retainer embedded with sensors to operate a computer and electric wheelchair simply by moving their tongues. ... > full story

Faulty fat sensor implicated in obesity and liver disease (February 19, 2012) -- Defects in a protein that functions as a dietary fat sensor may be a cause of obesity and liver disease, according to a new study. The findings highlight a promising target for new drugs to treat obesity and metabolic disorders. ... > full story

Surprising molecular switch: Lipids help control the development of cell polarity (February 19, 2012) -- In a standard biology textbook, cells tend to look more or less the same from all sides. But in real life cells have fronts and backs, tops and bottoms, and they orient many of their structures according to this polarity explaining, for example, why yeast cells bud at one end and not the other. ... > full story