ScienceDaily Health Headlines -- for Friday, December 23, 2011

ScienceDaily Health Headlines

for Friday, December 23, 2011

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New model to design better flu shots proposed (December 22, 2011) -- The flu shot, typically the first line of defense against seasonal influenza, could better treat the US population, thanks to new research. ... > full story

Built-in 'self-destruct timer' causes ultimate death of messenger RNA in cells (December 22, 2011) -- Researchers have discovered the first known mechanism by which cells control the survival of messenger RNA (mRNA) -- arguably biology's most important molecule. The findings pertain to mRNAs that help regulate cell division and could therefore have implications for reversing cancer's out-of-control cell division. ... > full story

Long intervening non-coding RNAs play pivotal roles in brain development (December 22, 2011) -- Scientists have identified conserved, long intervening non-coding RNAs that play key roles during brain development in zebrafish, and went on to show that the human versions of these RNAs can substitute for the zebrafish lincRNAs. Until now, lincRNAs have been studied primarily in cell lines rather than at the organismal level, which has precluded research into how lincRNAs affect growth and development. ... > full story

Starlings help explain irrational preferences (December 22, 2011) -- Research into decision-making by European starlings may help explain why many animals, including humans, sometimes exhibit irrational preferences. ... > full story

Brain size may predict risk for early Alzheimer's disease (December 22, 2011) -- New research suggests that, in people who don't currently have memory problems, those with smaller regions of the brain's cortex may be more likely to develop symptoms consistent with very early Alzheimer's disease. ... > full story

Personalized treatment for Crohn's Disease a step closer following gene mapping (December 22, 2011) -- Three new locations for Crohn's Disease genes have been uncovered using a novel gene mapping approach. ... > full story

Changes in London taxi drivers' brains driven by acquiring 'the Knowledge' (December 22, 2011) -- Acquiring 'the Knowledge' – the complex layout of central London's 25,000 streets and thousands of places of interest – causes structural changes in the brain and changes to memory in the capital's taxi drivers, new research has shown. ... > full story

Severe congenital disorder successfully treated in a mouse model for the first time (December 22, 2011) -- Using a mouse model, researchers have for the first time successfully treated a severe congenital disorder in which sugar metabolism is disturbed. Scientists demonstrated that if female mice are given mannose with their drinking water prior to mating and during pregnancy, their offspring will develop normally even if they carry the genetic mutation for the congenital disorder. ... > full story

Bone marrow and blood stem cell transplant survival rates equal, when donor is unrelated to patient (December 22, 2011) -- Patients who receive a blood stem cell transplant from a donor outside of their family to treat leukemia and other blood diseases are more likely to have graft failure but less likely to experience graft-versus-host disease, a condition caused by the donor cells attacking the recipient's body, if the transplanted blood cells come directly from a donor's bone marrow, rather than from blood stem cells circulating in the donor's bloodstream (PBSCs), according to new research. ... > full story

The mall as a sanctuary: Study finds holiday shopping outlets aren't just shrines to spending (December 22, 2011) -- An international study of holiday shopping and religion finds that dominant religious groups are more likely to experience "consumption mass hysteria" while shoppers in minority religions may view malls and stores much differently: as central meeting places that "can play an active role in the creation of a sacred event." ... > full story

Promising results in mice on needle-free candidate universal vaccine against various flu viruses (December 22, 2011) -- Scientists have discovered that an antigen common to most influenza viruses, and commonly referred to as matrix protein 2, when administered under the tongue could protect mice against experimental infection caused by various influenza viruses, including the highly pathogenic avian H5 virus and the pandemic H1 virus. ... > full story

Nanometer-scale growth of cone cells tracked in living human eye (December 22, 2011) -- Vision scientists have come up with a novel way to make the measurements in a living human retina by using information hidden within a commonly used technique called optical coherence tomography. ... > full story

We are natural born multi-taskers (December 22, 2011) -- Scientists have found that we are natural-born multi-taskers. They found evidence that we can pay attention to more than one thing at a time. ... > full story

Severe sepsis can lead to impairment of immune system, study suggests (December 22, 2011) -- An analysis of lung and spleen tissue from patients who died of sepsis revealed certain biochemical, cellular and histological findings that were consistent with immunosuppression, according to a new study. ... > full story

From heterogeneous patient measurements towards earlier diagnosis in Alzheimer's disease (December 22, 2011) -- Medical researchers have developed a decision support tool for objective diagnostics of Alzheimer's disease. The tool compares measurements of a patient to measurements of other persons available in large databases and provides a simple index about the severity of the disease. The project has shown that the tool improves the accuracy of diagnosis and clinicians' confidence about their decision, making earlier diagnosis possible. ... > full story

Which wheats make the best whole-grain cookie doughs? (December 22, 2011) -- Festive cookies, served at year-end holiday gatherings, may in the future be made with a larger proportion of whole-grain flour instead of familiar, highly refined white flour. ... > full story

Do you hear what I hear? Noise exposure surrounds us (December 22, 2011) -- Nine out of 10 city dwellers may have enough harmful noise exposure to risk hearing loss, and most of that exposure comes from leisure activities. ... > full story

Breakthrough in treatment to prevent blindness (December 21, 2011) -- A new study shows a popular treatment for a potentially blinding eye infection is just as effective if given every six months versus annually. This randomized study on trachoma, the leading cause of infection-caused blindness in the world, could potentially treat twice the number of patients using the same amount of medication. ... > full story

The biology behind severe PMS (December 21, 2011) -- Sensitivity to allopregnanolone, a hormone that occurs naturally in the body after ovulation and during pregnancy, changes during the course of the menstrual cycle and is different in women with severe PMS compared with women without PMS complaints. ... > full story

Pregnant women advised to stay cool for baby's sake: Australian study (December 21, 2011) -- Medical researchers have found a link between increases in temperature and the incidence of stillbirth and shorter pregnancies. ... > full story

Prejudice comes from a basic human need and way of thinking, new research suggests (December 21, 2011) -- Where does prejudice come from? Not from ideology, say the authors of a new article. Instead, prejudice stems from a deeper psychological need, associated with a particular way of thinking. People who aren't comfortable with ambiguity and want to make quick and firm decisions are also prone to making generalizations about others. ... > full story

How normal cells fuel tumor growth (December 21, 2011) -- A new study has discovered how normal cells in tumors can fuel cancer progression. The study examines what happens when normal cells called fibroblasts in tumors lose an important tumor-suppressor gene. The findings suggest new strategies for controlling tumor growth, they provide insight into the mechanisms that control the co-evolution of cancer cells and their surrounding normal cells in tumors, and they demonstrate how this gene normally suppresses cancer development. ... > full story

Model to foster new drug development to treat pain and epilepsy developed (December 21, 2011) -- Drawing on X-ray crystallography and experimental data, as well as a software suite for predicting and designing protein structures, a researcher has developed an algorithm that predicts what has been impossible to generate in the laboratory: the conformational changes in voltage-gated sodium channels when they are at rest or actively transmitting a signal in muscle and nerve cells. ... > full story

How pregnancy changes a woman's brain (December 21, 2011) -- We know a lot about the links between a pregnant mother's health, behavior, and moods and her baby's cognitive and psychological development once it is born. But how does pregnancy change a mother's brain? ... > full story

Cerebrospinal fluid test can pick up Alzheimer's before symptoms appear (December 21, 2011) -- Analysis of the cerebrospinal fluid can detect whether a person has Alzheimer’s disease before symptoms appear. Researchers have studied biomarkers that offer more reliable diagnosis and, in the longer term, the possibility of effective new treatments. ... > full story

Do our medicines boost pathogens? (December 21, 2011) -- Scientists have discovered a parasite that not only had developed resistance against a common medicine, but at the same time had become better in withstanding the human immune system. With some exaggeration: Medical practice helped in developing a superbug. For it appears the battle against the drug also armed the bug better against its host. ... > full story

Increase in resting heart rate over 10-year period linked with increased risk of heart disease death (December 21, 2011) -- In a study that enrolled nearly 30,000 apparently healthy men and women, those who had an increase in their resting heart rate over a 10-year period had an increased risk of death from all causes and from ischemic heart disease, according to a new study. ... > full story

Synesthesia linked to a hyper-excitable brain (December 21, 2011) -- Hyper-excitability' in regions of the brain may underlie synesthesia, an unusual condition where some people experience a 'blending of the senses', new researchers suggest. ... > full story

Single cell endoscope: Researchers use nanophotonics for optical look inside living cells (December 21, 2011) -- Researchers have developed a nanowire endoscope that can provide high-resolution optical images of the interior of a single living cell, or precisely deliver genes, proteins, therapeutic drugs or other cargo without injuring or damaging the cell. ... > full story

Hypertension treatment associated with long-term improvement in life expectancy (December 21, 2011) -- Patients with systolic hypertension who were treated with the diuretic chlorthalidone for 4.5 years as part of a clinical trial had a significantly lower rate of death and a gain in life expectancy free from cardiovascular death about 20 years later compared to patients who received placebo, according to a new study. ... > full story

New take on impacts of low dose radiation (December 21, 2011) -- Working with a special line of human breast cells, researchers have shown that for low dose levels of ionizing radiation cancer risks may not be directly proportional to dose. This contradicts the standard model for predicting biological damage from ionizing radiation, which holds that risk is directly proportional to dose at all levels of irradiation. ... > full story

Gene therapy for ears (December 21, 2011) -- Gene therapy may someday in the future replace the use of implants in deaf people. The carrier for this gene medicine may be derived from shrimp shells. ... > full story

Why humans are so sociable these days (December 21, 2011) -- Humans have evolved to become the most flexible of the primates and being able to live in lots of different social settings sets us apart from non-human primates, suggests new research. ... > full story

Can nerve growth factor gene therapy prevent diabetic heart disease? (December 21, 2011) -- New research has investigated if nerve growth factor gene therapy can prevent diabetic heart failure and small vascular disease in mice. ... > full story

Breastfeeding saved babies in 19th century Montreal (December 21, 2011) -- Breastfeeding increased infant survival rates in 19th -Century Montreal in two major ways, according to new research. Mother's milk protected vulnerable infants from food and water contaminated by fecal bacteria, while breastfeeding postponed the arrival of more siblings and that improved the health of mothers as well as their subsequent children. ... > full story

New device for rapid, mobile detection of brain injury (December 21, 2011) -- Scientists have created a handheld device capable of quickly detecting brain injuries such as hematomas. The prototype for the hematoma detection device is based on the concept of using instrumental motion as a signal in near-infrared imaging. ... > full story

Being told painting is fake changes brain's response to art (December 21, 2011) -- Being told that a work of art is authentic or fake alters the brain's response to the visual content of artwork, academics have found. ... > full story

Discovery may lead to safer treatments for asthma, allergies and arthritis (December 20, 2011) -- Scientists have discovered a missing link between the body's biological clock and sugar metabolism system, a finding that may help avoid the serious side effects of drugs used for treating asthma, allergies and arthritis. ... > full story

New candidate vaccine neutralizes all tested strains of malaria parasite (December 20, 2011) -- A new candidate malaria vaccine has the potential to neutralize all strains of the most deadly species of malaria parasite. ... > full story

Blood pressure medicines reduce stroke risk in people with prehypertension, study suggests (December 20, 2011) -- Blood pressure medicines reduced the risk of stroke by 22 percent in people with prehypertension. More than 50 million Americans have an increased risk of stroke due to prehypertension. ... > full story

Are the anxious oblivious? (December 20, 2011) -- Anxious study participants aren't as physiologically sensitive to subtle changes in their environment as less fearful individuals, new research shows. Researchers reason that anxious people could have a deficit in their threat evaluation capacities, which are necessary for effective decision-making and fear regulation. ... > full story

Human skull is highly integrated: Study sheds new light on evolutionary changes (December 20, 2011) -- Scientists studying a unique collection of human skulls have shown that changes to the skull shape thought to have occurred independently through separate evolutionary events may have actually precipitated each other. ... > full story

Scientists identify an innate function of vitamin E (December 20, 2011) -- It's rubbed on the skin to reduce signs of aging and consumed by athletes to improve endurance but scientists now have the first evidence of one of vitamin E's normal body functions. The powerful antioxidant found in most foods helps repair tears in the plasma membranes that protect cells from outside forces and screen what enters and exits, new research shows. ... > full story

Mediterranean diet gives longer life, Swedish study suggests (December 20, 2011) -- A Mediterranean diet with large amounts of vegetables and fish gives a longer life, according to Swedish research. A number of studies since the 1950s have shown that a Mediterranean diet, based on a high consumption of fish and vegetables and a low consumption of animal-based products such as meat and milk, leads to better health. ... > full story

The role of Internet pharmacies in prescription drug abuse (December 20, 2011) -- Efforts to halt the growing abuse of prescription drugs must include addressing the availability of these drugs on the Internet and increasing physician awareness of the dangers posed by Internet pharmacies, according to experts. ... > full story

Middle-age blood pressure changes affect lifetime heart disease, stroke risk (December 20, 2011) -- Changes in blood pressure during middle age can affect lifetime risk for heart disease and stroke. People who maintain or reduce their blood pressure to normal levels during middle age have the lowest lifetime risk of cardiovascular disease, while those with an increase in blood pressure have the highest risk. Age and duration of blood pressure changes can help determine individualized lifetime risk for -- and prevention of -- cardiovascular disease. ... > full story

Infectious fungus, thought to be asexual, isn't (December 20, 2011) -- Candida tropicalis turns out to have sex, making it the second medically important member of the genus to be capable of mating. Sex may improve the survival of the species, particularly when it's under pressure. It may also mean the species can achieve greater virulence or drug resistance more quickly than previously thought. ... > full story

Babies track word patterns long before word-learning starts (December 20, 2011) -- During the first year of life, when babies spend so much time listening to language, they're actually tracking word patterns that will support their process of word- learning that occurs between the ages of about 18 months and two years. ... > full story


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